Orthopaedic - Orthopaedic Surgeons including treatment for children under 12 years near Metamorfosi

Kakavas Pindaros is an Orthopedic Surgeon at the Athens Medical Center, Chief Physician of the AEK F.C. Football Academy, and maintains a private practice in Neo Psychiko. He holds a Diploma in Sports Injuries from the International Olympic Committee based in Lausanne. He graduated from the Medical School of Aristotle University of Thessaloniki and specialized in Orthopedics at the General Hospital "Evangelismos." Concurrently, he specialized in Upper Limb Microsurgery and Pediatric Orthopedics at the General Hospital of Attica "KAT." He has served as a consultant at the 2nd Sports Injuries Clinic of Euroclinic Athens, Team Doctor for AEK FC (A' Team), Football Academy Doctor for Panathinaikos F.C., and as a member of the medical staff for AEK BC and Panellinios BC. Throughout his career, he has accumulated surgical experience in sports injuries, arthroscopic surgery, total knee and hip arthroplasties, and orthopedic trauma.

Kontrarou Eugenia is an Orthopedic Surgeon with a private practice in Agia Varvara. She holds a postgraduate degree in Metabolic Bone Diseases - Osteoporosis from the National and Kapodistrian University of Athens. She is a member of the Athens Medical Association and the Hellenic Osteoporosis Foundation, specializing in sports injuries and osteoporosis. In her private practice, she offers a wide range of services tailored to the individual needs of each patient.

Triantafyllidis Pantelis is an Orthopedic Surgeon with a clinic located in Galatsi, Marousi. He specializes in Knee and Hip Arthroplasty, Robotic Arthroplasty, Arthroscopic surgery of the knee, shoulder, and ankle, the treatment of Sports injuries, Osteoporosis, and fracture management. Additionally, during his specialty training, he has been trained in Microsurgery and upper limb surgery, as well as Pediatric Orthopedics. The clinic treats adult and adolescent patients with all types of orthopedic problems. Concurrently, he serves as the Director and Scientific Supervisor of the orthopedic department at Orthobiomed. He performs surgeries and collaborates with major hospitals in Athens, such as "Hygeia," where he also served as Deputy Director, and Mitera. He graduated from the Medical School of the University of Ioannina, holds a specialty title in Orthopedic Surgery from the Orthopedic Clinic of the University of Athens at KAT Hospital, and is a PhD candidate at the Medical School of the National and Kapodistrian University of Athens. He has participated in the education of students in Orthopedics and the first aid laboratory for Physiotherapy students. He has served as a physician for various teams and sports clubs and has operated on numerous athletes. He has participated as a speaker and organizer in numerous conferences, lectures, and presentations in Greece and abroad, as well as in writing articles for Greek and international scientific journals. Finally, he is a member of many Greek and international scientific societies.

Markopoulos Xristos is an Orthopedic Surgeon and a PhD candidate at the Medical School of the University of Athens, with a private practice in Marousi. Concurrently, he serves as a Consultant in the Upper Limb and Microsurgery Department at YGEIA Hospital and has been a member of the medical team for the Panathinaikos BC basketball team. He graduated from the Medical School of the University of Eastern Piedmont in Northern Italy and subsequently specialized in Orthopedic Surgery at the 1st University Orthopedic Clinic of the University of Athens at "Attiko" Hospital. During his specialization, he focused particularly on the Pediatrics and Microsurgery departments at KAT Hospital. Additionally, he holds a postgraduate degree in Metabolic Bone Diseases - Osteoporosis from the National and Kapodistrian University of Athens. He is also a member of the Hellenic Osteoporosis Society and the Hellenic Pain Society. Finally, he has contributed to scientific papers and textbooks that have been presented at conferences and published in journals.

Athanasopoulos Konstantinos MD, MSc is an Orthopedic Surgeon maintaining private practices in Piraeus and Galata Troizinia, while also collaborating with the Athens Medical Group (Peristeri clinic) and the sports injury center at Mediterraneo Hospital. He is certified in robotic knee and hip arthroplasty using the most advanced robotic system worldwide, the only one with FDA certification in the USA for robotic total joint revision arthroplasty. He holds a postgraduate degree in “Metabolic Bone Diseases” from the Medical School of Athens and graduated in Medicine from the University of Medicine and Pharmacy "Carol Davila". He specialized in Orthopedics and Traumatology at the General Hospital of Piraeus “Tzaneio” and in Pediatric Orthopedics at the Children’s Hospital "P. & A. Kyriakou", and after successful examinations where he ranked first in Attica, he obtained the title of orthopedic specialty. He served as an instructor at the Special Training Center for Health Professionals in the Orthopedics and Traumatology department of the General Hospital of Piraeus "Tzaneio" regarding the implementation of a preventive screening program for scoliosis and other spinal deformities in students. Additionally, he has participated as a speaker and trainee in numerous conferences and seminars in Greece. His areas of expertise include arthroscopic surgery, robotic knee and hip arthroplasty, as well as robotic knee and hip revision surgery with Fast-Track ERAS protocols for rapid return to activities, and minimally invasive surgery.

Ioannis Mamais is an Orthopedic Surgeon with a private practice in Ano Patissia. He holds a medical degree from the University of Belgrade and specialized in Orthopedics. He has extensive and significant clinical experience, having worked as an Orthopedic Surgeon – Consultant in the Reconstructive Surgery Clinic at the Athens Medical Group (P. Faliro Clinic), at the General Hospital "Red Cross," and at the Pediatric Hospital "P. & A. Kyriakou." Furthermore, he specializes in arthroscopy, traumatology, and hip and knee arthroplasty.

Ο Δρ. Νικόλαος Καλύβας είναι Ορθοπαιδικός Χειρουργός με 15ετή εμπειρία στο Σύστημα Υγείας της Γερμανίας (2010–2025). Απο το 2026 διατηρεί ιδιωτικό ιατρείο στους Αμπελόκηπους (έναντι της αμερικανικής πρεσβείας). Για περισσότερα από 15 έτη εργάστηκε σε κλινικές υψηλού επιπέδου της Γερμανίας, ενώ από το 2017 υπηρέτησε ως Επιμελητής και από το 2021 ως Αναπληρωτής Διευθυντής σε πιστοποιημένο κέντρο ενδοπροσθετικής (EPZmax), διενεργώντας συνολικά πάνω από 11.000 χειρουργικές επεμβάσεις.

Εξειδικεύεται σε αρθροπλαστική Ισχίου με τεχνική AMIS, ρομποτική και εξατομικευμένη Αρθροπλαστική Γόνατος, αρθροπλαστική Ώμου με ελάχιστα επεμβατική προσπέλαση και αρθροσκοπική Χειρουργική Ώμου & Γόνατος.

Εφαρμόζει πρωτόκολλα ταχείας αποκατάστασης (Rapid Recovery – Fast Track) με στόχο την άμεση κινητοποίηση και την ασφαλή επάνοδο των ασθενών. Διαθέτει επιπλέον εξειδίκευση στην Αθλητιατρική, τη Χειροθεραπεία και την υπερηχογραφική διάγνωση του μυοσκελετικού συστήματος, καθώς και στον έλεγχο ισχίων νεογνών κατά Graf. Στη διαγνωστική του προσέγγιση αξιοποιεί συστηματικά τη δεξιότητά του στην υπερηχογραφία μυοσκελετικού, επιτρέποντας άμεση, δυναμική και στοχευμένη αξιολόγηση των παθήσεων.

Η εξειδίκευσή του στην Αθλητιατρική και τη Χειροθεραπεία διαμόρφωσε μια πιο ολιστική και λειτουργική προσέγγιση απέναντι στον ασθενή. Ο Δρ. Καλύβας δίνει προτεραιότητα στη συντηρητική θεραπεία, η οποία περιλαμβάνει εξατομικευμένα πρωτόκολλα αποκατάστασης καθώς και υπερηχογραφικά καθοδηγούμενες εγχύσεις κορτιζόνης, υαλουρονικού οξέος και PRP (Platelet Rich Plasma).

Εφόσον έχει εξαντληθεί κάθε πιθανότητα βελτίωσης της πάθησης του ασθενούς με συντηρητική θεραπεία, προτείνει τη χειρουργική αντιμετώπιση μόνο όταν αυτή είναι πραγματικά απαραίτητη.

Στόχος του είναι η παροχή ιατρικής φροντίδας ευρωπαϊκού επιπέδου, με ασφάλεια, διαφάνεια και σεβασμό στον ασθενή.

Dr. Lepetsos Panagiotis is an Orthopedic Surgeon and maintains his private practice in Neo Irakleio. He is a consultant at the Athens Medical Center. The physician graduated from the Medical School of the University of Athens, holds a Master's Degree in Metabolic Bone Diseases, and a PhD in Knee Osteoarthritis. He has worked and specialized in the 4th Orthopedic Clinic of KAT Hospital, the Microsurgery Clinic of KAT Hospital, as well as the Pediatric Orthopedic Clinic of the "Agia Sofia" Children's Hospital. He has specialized in reconstructive hip and knee surgery through a salaried fellowship of the International Society of Orthopaedic Surgery and Traumatology (SICOT). He has worked as a consultant at KAT Hospital (2017 – 2019). He has more than 50 publications in international scientific journals and more than 200 presentations and lectures at international and Greek orthopedic conferences. He has been awarded five times by the Hellenic Orthopedic Society. He is a reviewer for 40 international scientific journals. He has participated in numerous seminars and scientific conferences in Greece and abroad.

Pathiakis Ioannis Md, MSc, PhD is an Orthopedic Surgeon who maintains a private practice in Peristeri. He holds a medical degree from the Medical School of the National and Kapodistrian University of Athens and has obtained two postgraduate degrees in "Minimally Invasive Surgery, Robotic Surgery & Tele-surgery Medicine" and "Surgical Anatomy" from the Medical School of the same university. Additionally, he holds a Doctorate from the National and Kapodistrian University of Athens in the Department of Anatomy. He is specialized in Robotic Knee and Hip Surgery and in Microsurgical Bloodless Carpal Tunnel Release and holds a diploma in Medical Acupuncture from the Scientific Association of Medical Acupuncturists of Greece. He has completed training at numerous hospitals, while his specialty was completed in General Surgery at the General Hospital of Ierapetra. Furthermore, during his career, he has taught courses on First Aid, Traumatology, and musculoskeletal injuries at the IEK of Siteia and at the Volunteer Corps of Samaritans and Rescuers of Siteia, respectively. Finally, as part of his continuous education and updating in microsurgery and medical acupuncture, the physician regularly attends medical conferences, earning personal honorary distinctions.

Beyond Medicine, he holds a degree in Social Theology from the Theological School of Athens.

Mitrogiannis Georgios is an Orthopedic Surgeon specializing in Adults and Pediatrics – Sports Medicine Physician, maintaining a private practice in Nea Ionia. Concurrently, he works as a Consultant in the Pediatric Orthopedic Clinic at IASO Children’s Hospital. He holds a medical degree from the University of Ioannina School of Medicine and is a doctoral candidate at the School of Medicine, National and Kapodistrian University of Athens. He completed his specialty training in Orthopedics and Traumatology at the General Children’s Hospital "Panagiotis & Aglaia Kyriakou," the Korgialenio-Benakio Greek Red Cross Hospital, and the General Athens Hospital "Evangelismos," where, following the receipt of his Orthopedic Specialty certification, he remained for an additional two years as a Specialist Orthopedic Surgeon. During his residency, he received extensive training in managing injuries of all severities, sports-related injuries, and arthroplasties, actively participating in a large number of surgical procedures across the full spectrum of Orthopedics. He holds the Barca Innovation Hub Professional Diploma in Team Sports Injuries and the FIFA Diploma in Football Medicine, confirming his advanced expertise in sports medicine. In 2023, he served as a physician for the AEK Football Club, and from September 2024 to the present, he has been the team physician for the Academies of Panathinaikos Football Club. He also has a robust scientific portfolio with publications and presentations at Greek and international medical conferences and journals.

Dr. Panagopoulos Georgios is a Director Orthopedic Surgeon with extensive training and surgical experience in the United States of America and the United Kingdom. Although he is involved in the entire spectrum of Orthopedic Surgery, his primary area of expertise/interest is Arthroscopic and Reconstructive Surgery of the Upper Limb (shoulder, elbow, and hand). Dr. Panagopoulos has completed numerous long-term fellowship programs in the upper limb and has served at the highest level as a Consultant Orthopedic Surgeon at one of the largest Trauma Centers in Europe. Dr. Panagopoulos was born and raised in Athens. He completed his medical studies at the Medical School of the University of Rome, graduating with honors (magna cum laude). Subsequently, he completed his Residency in Orthopedic Surgery & Traumatology at the University Orthopedic Clinic of the University of Athens (Attikon University General Hospital). Dr. Panagopoulos expanded his training by completing a fellowship program in the Upper Limb in Pittsburgh, USA (2016-2017). He then served at the world-renowned Shoulder-Elbow Clinic in Reading, United Kingdom (2018-2020), as well as at the Royal National Orthopaedic Hospital in Stanmore (2020). Dr. Panagopoulos subsequently worked as a Consultant Orthopedic Surgeon at the Royal London Hospital, one of the largest Trauma Centers in the United Kingdom and Europe. He holds a PhD from the Medical School of the National and Kapodistrian University of Athens.

Dr. Paraskeuakos Grigorios is an Orthopedic Surgeon who has maintained a private practice in Nikaia since 2005. He is a graduate of the Medical School of the National and Kapodistrian University of Athens and completed his residency at the General Hospital of Attica KAT. Additionally, he specialized in General Surgery in the Pediatric Surgery Department of the General Hospital of Piraeus "Tzaneio" and further specialized in the Microsurgery Department of the General Hospital of Attica KAT. The physician continuously updates his knowledge in orthopedic matters through ongoing participation in osteoporosis and general orthopedics seminars both in Greece and abroad. Finally, his private clinic offers a wide range of services, tailored to the individual needs of each patient.

Ο Δρ. Κασιμάτης Γεώργιος MD, PhD, FEBOT, FEBHS είναι Ορθοπαιδικός Χειρουργός με ιδιωτικά ιατρεία στο Νέο Ηράκλειο και το Μαρούσι. Μετά την ειδικότητά του ολοκλήρωσε το Διδακτορικό του στο Πανεπιστήμιο Πατρών με "Άριστα" πάνω στη σπονδυλική στήλη. Εξειδικεύθηκε σε μεγάλα κέντρα του εξωτερικού πάνω σε επεμβάσεις αποκατάστασης των οστών και των αρθρώσεων και έλαβε τον τίτλο του “Fellow” από την Ευρωπαϊκή Εταιρεία Ορθοπαιδικής και Τραυματολογίας (FΕΒΟΤ) κατόπιν γραπτών και προφορικών εξετάσεων. Στη συνέχεια και για μια πενταετία ασχολήθηκε με το ‘Ανω Άκρο – Μικροχειρουργική και το 2012 κατόπιν γραπτών και προφορικών εξετάσεων που διεξήγαγε ο επίσημος φορέας της Ευρωπαϊκής Ένωσης για τη Χειρουργική του Χεριού (FESSH/UEMS) στην Αμβέρσα (Βέλγιο), πιστοποιήθηκε στη Χειρουργική του Χεριού ως “Fellow of the European Board in Hand Surgery” (FEBHS). Την πιστοποίηση αυτή ακόμα και σήμερα κατέχουν ελάχιστοι Έλληνες oρθοπαιδικοί χειρουργοί. Έχει ασχοληθεί επισταμένα με το αντικείμενο του ώμου και έχει δημοσιεύσεις σε έγκριτα σχετικά επιστημονικά περιοδικά, ενώ είναι και τακτικό μέλος της Ευρωπαϊκής Εταιρείας Ώμου-Αγκώνα (SECEC/ ESSSE). Στο ιατρείο του ο κάθε ασθενής ανεξάρτητα με την ηλικία του έχει τη δυνατότητα να ενημερωθεί για την πρόληψη-θεραπεία ορθοπαιδικών παθήσεων, σύμφωνα με τις πλέον σύγχρονες και εξειδικευμένες μεθόδους. Ο Δρ. Κασιμάτης Γεώργιος, FEBOT, FEBHS έχει σημαντική εμπειρία σε περιστατικά αρθροσκοπήσεων και αρθροπλαστικών (γόνατος, ισχίου, ώμου), ενώ αναλαμβάνει παιδιά με ορθοπαιδικά προβλήματα, καθώς και ασθενείς με προβλήματα μυοσκελετικής ογκολογίας. Οι ορθοπαιδικές υπηρεσίες που παρέχονται στο ιατρείο του είναι μεταξύ άλλων: παρακολούθηση κατάγματος, παρακολούθηση κύφωσης, παρακολούθηση σπονδυλόλυσης – σπονδυλολίσθησης, παρακολούθηση σκολίωσης, έλεγχος οστεοπόρωσης, τοποθέτηση γύψου και ενδοαρθρικές ενέσεις. Τα τελευταία χρόνια ασχολείται ιδιαίτερα με τις νεότερες τεχνικές ελάχιστης παρεμβατικότητας για τη θεραπεία των μυοσκελετικών παθήσεων και κακώσεων, συμπεριλαμβανομένων της αρθροσκόπησης, της διαδερμικής οστεοσύνθεσης, αλλά και των αρθροπλαστικών ταχείας ανάρρωσης (Fast-Track Arthroplasty).

Orthopedic Surgeon Mpekas Georgios maintains private clinics in Pangrati, Agioi Anargyroi, and Palaio Faliro. He graduated from the Medical School of the National and Kapodistrian University of Athens and subsequently attended a postgraduate program in Metabolic Bone Diseases. He specialized in General Surgery at the General Hospital of Messolonghi "Chatzikosta" and in Orthopedics at the General Hospital "Asklipieio" Voula and the Children's General Hospital "Panagiotis & Aglaia Kyriakou," where he also engaged in Pediatric Orthopedics. Additionally, he completed a six-month specialization in the Microsurgery - Upper Limb department at the Attica General Hospital KAT. He has worked as an Orthopedic Surgeon Consultant at Metropolitan Hospital. The physician holds an Advanced Life Trauma Support diploma and is a member of the Hellenic Osteoporosis Foundation. Besides his private clinics in Pangrati and Agioi Anargyroi, Mpekas Georgios also works as an Orthopedic Surgeon at the Athens Medical Center (Marousi Clinic) and as an Associate Orthopedic Surgeon at the private clinic REA. Concurrently, he works as a Pediatric Orthopedic Consultant at the Pediatric Center of Athens (Athens Medical Group). The physician approaches each case with particular sensitivity, providing appropriate treatment tailored to the specific needs of each patient and their condition. He undertakes the surgical management of emergency orthopedic cases (fractures). Furthermore, his medical team manages numerous elective orthopedic surgical cases (arthroscopies, total arthroplasties, upper limb microsurgery, sports injuries). Finally, modern biological therapies (PRP, hyaluronic acid and cortisone injections) are performed in the clinic.

Ο Χρηστογεώργος Πάρις, MD, MSc είναι Ορθοπαιδικός Χειρουργός και Τραυματολόγος με εξειδίκευση στις παθήσεις και τη Χειρουργική της Σπονδυλικής Στήλης. Ο ιατρός είναι απόφοιτος της Ιατρικής Σχολής του Πανεπιστημίου Κρήτης και κάτοχος Μεταπτυχιακού Διπλώματος (Master of Science, MSc) στην «Άθληση και Υγεία» με βαθμό Άριστα από την Ιατρική Σχολή Αθηνών του Εθνικού και Καποδιστριακού Πανεπιστημίου Αθηνών. Εκπλήρωσε την ειδίκευσή του στη Γενική Χειρουργική στο 251 Γενικό Νοσοκομείο Αεροπορίας (2014-2015). Ξεκίνησε και ολοκλήρωσε την ειδίκευσή του στην Ορθοπαιδική Χειρουργική και Τραυματολογία στο Γενικό Νοσοκομείο Αθηνών «Γ. Γεννηματάς» (2016-2021), όπου απέκτησε ιδιαίτερη εμπειρία στη διάγνωση και χειρουργική αντιμετώπιση σύνθετων καταγμάτων, κακώσεων, χρόνιων εκφυλιστικών παθήσεων και παραμορφώσεων του άνω και του κάτω άκρου . Στο πλαίσιο της ειδικότητας, εκπαιδεύτηκε στο Τμήμα Σκολίωσης και Σπονδυλικής Στήλης του Γ.Ν.Α. «ΚΑΤ» (2019-2020), όπου απέκτησε εμπειρία στην ολοκληρωμένη αντιμετώπιση όλου του φάσματος των παθήσεων, σύνθετων παραμορφώσεων και κακώσεων της Σπονδυλικής Στήλης. Ακόμα, εκπαιδεύτηκε στην Παιδο-ορθοπαιδική στο Νοσοκομείο Παίδων «η Αγία Σοφία» (2020-2021), όπου ήρθε σε επαφή με μεγάλο όγκο κακώσεων και παραμορφώσεων του παιδιατρικού πληθυσμού. Ο ιατρός εκπαιδεύτηκε ως Fellow στο Centre for Spinal Studies and Surgery του Queen’s Medical Centre, Nottingham University Hospitals στο Nottingham του Ηνωμένου Βασιλείου (2023), το οποίο αποτελεί διεθνώς αναγνωρισμένο Κέντρο Αριστείας κι Αναφοράς για τις παθήσεις, παραμορφώσεις και κακώσεις της Σπονδυλικής Στήλης στο Ηνωμένο Βασίλειο, καθώς και Κέντρο Εκπαίδευσης της AO Spine. Σήμερα, ο ιατρός εργάζεται ως Επιμελητής Ορθοπαιδικός- Χειρουργός Σπονδυλικής Στήλης στην Κλινική Σπονδυλικής Στήλης, Κέντρο Σκολίωσης, Τραύματος και Ογκολογίας Σπονδυλικής Στήλης του Νοσοκομείου Metropolitan General στην Αθήνα. Είναι διδάσκων του σεμιναρίου «Πρώτες βοήθειες- ορθοπαιδικά επείγοντα» για προπτυχιακούς και μεταπτυχιακούς φοιτητές της Ιατρικής Σχολής Αθηνών, ΕΚΠΑ από το 2019 έως σήμερα και ομιλεί άπταιστα Αγγλικά και Γερμανικά. Συμμετέχει ενεργά σε εγχώρια και διεθνή συνέδρια καθώς και επιμορφωτικά σεμινάρια και παράγει ερευνητικό έργο. Τέλος, είναι μέλος της Ελληνικής Εταιρίας Χειρουργικής Ορθοπαιδικής και Τραυματολογίας (Ε.Ε.Χ.Ο.Τ.) καθώς και του Ιατρικού Συλλόγου της Μεγάλης Βρετανίας (G.M.C.).

Dr Spiliotopoulos Georgios is a graduate of Medical School and a PhD candidate in Orthopedics at the University of Patras. He specialized at the 401 General Military Hospital of Athens and further specialized in Orthopedic Sports Medicine and modern minimally invasive surgical corrective techniques (MIS). Since 2018, he has been a Forensic Orthopedic Expert (technical consultant) for major insurance companies. He maintains a clinic in Neo Psychiko and is the head of the surgical team OrthoSoma (Ortho-Body).

Stathopoulos Ioannis MD, MSc is an Orthopedic Surgeon with a private practice in Ilioupoli. He is a graduate and PhD candidate of the Medical School of the National and Kapodistrian University of Athens, and he obtained a postgraduate degree in Metabolic Bone Diseases from the same university. He works as an Attending Orthopedic Surgeon in the Emergency Department of the Athens Medical Center in Marousi and concurrently collaborates with the Joint Reconstruction Clinic at the Athens Medical Center. His specialization focuses on total hip and knee arthroplasties, trauma, and osteoporosis. He has a substantial body of published work in both international and Greek scientific journals and books and has served as a reviewer for scientific articles in international journals. He closely follows advancements in his field and has participated in numerous conferences and seminars, many of which he attended as a speaker. Finally, he is a member of the Athens Medical Association, the Hellenic Osteoporosis Foundation, the Hellenic Society of Orthopedic Surgery and Traumatology, and the Hellenic Society for Bone Metabolism Research.

Dimitrios Mpazios is an Orthopedic Surgeon - Traumatologist with a private practice in Peristeri. He is a graduate of the Medical School of the University of Ioannina. The doctor specializes in arthroplasty, arthroscopy, sports injuries, spinal disorders, pediatric orthopedics, and traumatology. Additionally, patients can visit his modern clinic for conditions such as sports injuries, cervical syndrome, sciatica, shoulder dislocation, anterior cruciate ligament and meniscus tears, spinal stenosis, scoliosis and kyphosis, osteoarthritis of the knee, hip, and shoulder, herniated disc, among others. Finally, his specialized services include meniscus, cruciate ligament, and chondropathy arthroscopy, osteoporosis screening, intra-articular injections, cast application, as well as monitoring of kyphosis, spondylolysis, and spondylolisthesis.